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Clinical study on the changes of serum brain natriuretic peptide,C reactive protein and glycosylated hemoglobin in patients with diabetes and hypertension complicated with heart failure with preserved ejection fraction
Author(s): 
Pages: 140-141
Year: Issue:  13
Journal: Chinese Community Doctors

Keyword:  Heart failure with preserved ejection fractionDiabetesHypertension;
Abstract: Objective:To investigate the significance of the changes of serum brain natriuretic peptide,C reactive protein and glycosylated hemoglobin in patients with diabetes and hypertension complicated with heart failure with preserved ejection fraction.Methods:241 cases of HFPEF patients with hypertension and(or) diabetes were divided into the diabetic group and the non-diabetic group.The Hb A1 c,C reactive protein,NT-pro BNP of the two groups were compared.Results:The Hb A1 c,C reactive protein,NT-pro BNP and the incidence of major adverse cardial events(MACE) in the diabetic group were significantly higher than those in the non-diabetic group(P<0.05).There were positive correlation between Hb A1 cC reactive protein,NT-pro BNP and the incidence of MACE.Conclusion:NT-pro BNP, Hb A1 c,C reactive protein had higher clinical application value in predicting the incidence of diabetes and hypertension complicated with heart failure with preserved ejection fraction.
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