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Clinical study on the changes of serum brain natriuretic peptide,C reactive protein and glycosylated hemoglobin in patients with diabetes and hypertension complicated with heart failure with preserved ejection fraction
Author(s): Zhao Yingli, Li Zhijuan, The Second Department of Cardiology, the First Hospital Affiliated to Nanyang Medical College, Henan Province, Department of Cardiology, the First Hospital Affiliated to Henan University of Science and Technology in Luoyang City, Henan Province
Pages: 140-
141
Year: 2016
Issue:
13
Journal: Chinese Community Doctors
Keyword: Heart failure with preserved ejection fraction; Diabetes; Hypertension;
Abstract: Objective:To investigate the significance of the changes of serum brain natriuretic peptide,C reactive protein and glycosylated hemoglobin in patients with diabetes and hypertension complicated with heart failure with preserved ejection fraction.Methods:241 cases of HFPEF patients with hypertension and(or) diabetes were divided into the diabetic group and the non-diabetic group.The Hb A1 c,C reactive protein,NT-pro BNP of the two groups were compared.Results:The Hb A1 c,C reactive protein,NT-pro BNP and the incidence of major adverse cardial events(MACE) in the diabetic group were significantly higher than those in the non-diabetic group(P<0.05).There were positive correlation between Hb A1 cC reactive protein,NT-pro BNP and the incidence of MACE.Conclusion:NT-pro BNP, Hb A1 c,C reactive protein had higher clinical application value in predicting the incidence of diabetes and hypertension complicated with heart failure with preserved ejection fraction.
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