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Clinical Significance of C-reactive Protein and Heat Shock Protein 27 in Stress Response of Patients with Atrial Fibrillation
Pages: 200-203
Year: Issue:  5
Journal: Journal of Liaoning College of Traditional Chinese Medicine

Keyword:  atrial fibrillationheat shock protein 27C-reactive protein;
Abstract: Objective:To study the expression and clinical significance of heat shock protein 27(HSP27)and C-reactive protein(CRP)in stress response of patients with atrial fibrillation(AF)for different ages. Methods:Set in line with the western medicine diagnostic criteria of 60 patients with atrial fibrillation,according to the different age groups were divided into group A(60-69 years)20 cases,18 cases group B(70-79),group C(80-89)22 cases,21 cases of normal control group. In patients with atrial fibrillation attack on the day of the venous blood 4 ml,using enzyme-linked immunoassay(ELISA)determination of CRP and HSP27 concentration respectively,and compare the serum levels of CRP and HSP27 differences between groups. Results:A,B,C three groups of HSP27 level than the control group were significantly higher(P<0.01),group B and C,A HSP27 level is similar between the two groups is not obvious(P st13 0.05),HSP27 concentration higher than that of group A and group C(P<0.01). Group A and group C CRP levels higher than the control group significantly(P<0.01),while group B trend of CRP were elevated compared with control group,but no statistical significance(P=0.078),compared with A,B two group C were significantly elevated CRP levels(P<0.01),A,B two groups was no significant difference(P=0.261). Conclusion:The occurrence of atrial fibrillation may be associated with inflammation,inflammatory factors level is higher,the higher the risk of atrial fibrillation. HSP27 and CRP levels on the occurrence of atrial fibrillation and maintain plays an important role,especially in which the expression of HSP27 significance,can be used as a prediction index of af.
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