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Effect of Zhongjing Wenwei Granule on Chronic Atrophic Gastritis Rat Model induced by Ammonia Water
Pages: 34-36
Year: Issue:  5
Journal: Journal of Liaoning College of Traditional Chinese Medicine

Keyword:  Zhongjing Wenwei Granulechronic atrophic gastritispepsingastric acidgastrin;
Abstract: Objective:To study the effect of Zhongjing Wenwei Granule(ZJWW)on chronic atrophic gastritis rat model induced by ammonia water. Methods:SPF Wistar rat were drinked 0.025% ammonia water for 90 days,athomorphology,gastric acid,pepsin activity and gastrin production in serum and inflammatory cells number were observed in ammonia-induced chronic gastritis model on rats treatment by ZJWW. Results:ZJWW significantly increased gastric acid,pepsin activity and gastrin production in serum,decreased inflammatory cells number in ammonia-induced chronic gastritis model on rats,meantime,ZJWW could also recover pathological changes of gastric tissue in model rats. Conclusions:ZJWW have therapeutical effect on chronic gastritis model of rats.
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