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Clinical observation of Ningmitai Capsules combined with ceftriaxone sodium in treatment of acute pyelonephritis
Author(s): 
Pages: 492-495
Year: Issue:  4
Journal: World Phytomedicines

Keyword:  Ningmitai CapsulesCeftriaxone Sodium for injectionacute pyelonephritis;
Abstract: Objective To explore the clinical effect of Ningmitai Capsules combined ceftriaxone sodium in treatment of acute pyelonephritis. Methods Patients(234 cases) with acute pyelonephritis in Dujiangyan Traditional Chinese Medicine Hospital from December 2012 to September 2015 were randomly divided into control(n=114) and treatment(n=120) groups. Patients in the control group were iv administered with Ceftriaxone Sodium for injection, 2 g added into normal saline 250 m L, once daily. Patients in the treatment group were po administered with Ningmitai Capsules on the basis of control group, 4 grains/time, three times daily. The patients in two groups were treated for 2 weeks. After treatment, the efficacies were evaluated, and the disappeared times of clinical symptoms such as urinary irritation symptoms and fever was compared. Results After treatment, the efficacies in the control and treatment groups were 88.6% and 91.7%, respectively, and there was difference between groups(P < 0.05). After treatment, the disappeared times of urinary irritation symptoms, backache, and fever in the treatment group were shorter than those in the control group, and there were differences in two groups(P < 0.05). After treatment, urine red blood cell and white blood cell count in two groups were significantly decreased, and the difference was statistically significant in the same group(P < 0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups(P < 0.05). Conclusion Ningmitai Capsules combined ceftriaxone sodium has clinical curative effect in treatment of acute pyelonephritis, can significantly improve clinical symptoms such as urinary frequency, urine pain, which has a certain clinical application value.
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