The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
Clinical study on Shenfukang Capsules combined with sodium ferulate in treatment of chronic glomerulonephritis
Author(s): 
Pages: 496-499
Year: Issue:  4
Journal: World Phytomedicines

Keyword:  Shenfukang capsuleSodium Ferulate for injectionchronic glomerulo nephritis;
Abstract: Objective To investigate the effect of Shenfukang Capsules combined with Sodium Ferulate for injection in treatment of chronic glomerulonephritis. Methods Patients(72 cases) with chronic glomerulonephritis in Department of Neurology of Chengdu Xinhua Hospital from 2015 January to 2016 January were randomly divided into control and treatment groups using the computer method, and each group had 36 cases. The patients in the control group were iv administered with Sodium Ferulate for injection, 0.3 g added into 5% glucose Injection 250 m L, once daily. The patients in the treatment group were po administered with Shenfukang Capsules on the basis of control group, 1.5 g /time, three times daily. The patients in two groups were treated for 1 month. After treatment, the clinical efficacies were evaluated, and the changes of Scr, BUN, 24 h urine protein, RBC, and β2-MG, and levels of t-PA and PAI-1 in serum before and after treatment in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 74.52% and 94.44%, respectively, and there were differences between two groups(P < 0.05). After treatment, Scr, BUN, 24 h Upro, RBC, and β2-MG in two groups were significantly decreased, and the difference was statistically significant in the same group(P < 0.05). After treatment, the observational indexes in the treatment group were significantly decreased than those in the control group, with significant difference between two groups(P < 0.05). After treatment, levels of t-PA in two groups were significantly increased, PAI-1 was significantly decreased, and the difference was statistically significant in the same group(P < 0.05). After treatment, the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups(P < 0.05). Conclusion Shenfukang Capsules combined with Sodium Ferulate for injection has clinical curative effect in treatment of chronic glomerulonephritis, not only can improve renal function in patients, but also can elevate the level of serum t-PA, decrease the levels of PAI-1, and decrease urinary protein, is beneficial to improve symptoms in patients with chronic glomerulonephritis, which has a certain clinical application value.
Related Articles
No related articles found