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The application of both kinds of preemptive analgesia in prostatectomy
Author(s): WANG Jun, YU Dahai, WANG Keming, GAO Baozhu
Pages: 516-
518
Year: 2002
Issue:
4
Journal: JOURNAL OF TIANJIN MEDICAL UNIVERSITY
Keyword: 前列腺切除术; 超前镇痛; 中枢敏化;
Abstract: 目的:在前列腺切除术中,比较静脉和硬膜下隙给予亚麻醉剂量氯胺酮的超前镇痛作用.方法:30例择期前列腺切除手术病人随机分为3组.手术切皮前15 rmin给药,Kiv组:氯胺酮0.5 mg.kg1用生理盐水稀释至10 ml,1 min内静脉推注;Kepi组:氯胺酮0.5 mg.kg1用生理盐水稀释至10 ml,1 min内注入硬膜下隙导管;对照组:生理盐水10 ml,1 min内静脉推注.结果:各组VAS评分比较,术后Kepi组VAS评分明显低于Ctr组.术后FDAT比较,Kiv组和Kepi组明显长于对照组.术后48 h吗啡用量各实验组用量显著少于对照组.结论:术前应用亚麻醉剂量氯胺酮延长术后镇痛时间、减少术后吗啡用量,有超前镇痛作用.氯胺酮经硬膜下隙途径给药是一种有效的超前镇痛方法.
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