The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Dosimetric comparison of three- dimensional conformal radiotherapy and intensity modulated radiotherapy for III-stage non-small cell lung cancer
Author(s): 
Pages: 198-203
Year: Issue:  2
Journal: Chinese Journal of Medical Physics

Keyword:  non-small cell lung cancerthree-dimensional conformal radiotherapyintensity modulated radiotherapydosimetry;
Abstract: Objective To provide a reliable treatment basis for selecting the appropriate radiotherapy by comparing the dose differences of target volumes and organs at risk between three-dimensional conformal radiotherapy(3D-CRT) and intensity modulated radiotherapy(IMRT) for III-stage non-small cell lung cancer(NSCLC). Methods Sixteen patients with III-stage NSCLC were selected, and Pinnacle V9.2 treatment planning system was applied to design 3D-CRT and IMRT plans for each patient. The conformity index and homogeneity index of target volumes, and dose distribution of normal tissue were compared. Results The conformity indexes of IMRT and 3D-CRT plans were respectively 0.97 ± 0.02 and 0.91 ± 0.04; the homogeneity indexes of IMRT and 3D-CRT plans were respectively 0.16±0.06 and 0.20±0.14, with statistically significant differences(P<0.05). The dose parameters of organs at risk of IMRT plan were all lower than those of 3D-CRT plan in different degrees, except V5 and V10of lung tissue. Conclusion Compared with 3D-CRT, IMRT for III- stage NSCLC provides significant improvement in conformity and homogeneity, effectively lowers the radiation dose of normal tissue,and lowers the possibility of complication after the radiotherapy.
Related Articles
loading...