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One pot synthesis of 1-(((5-methylisoxazol-3-yl)amino) (phenyl)- methyl)naphthalen-2-ol in water
Pages: 54-56
Year: Issue:  1
Journal: Chemical Research

Keyword:  5-methyl-3-aminoisoxazoleone -potaqueous mediumcondensation reaction;
Abstract: In the presence of sodium sulfate ,using environmental‐friendly water as solvent ,1‐(((5‐methylisoxazol‐3‐yl)amino)‐(phenyl)‐methyl)naphthalen‐2‐ol was synthesized in one‐pot by the reaction of benzealdehyde ,2‐naphthol and 5‐methyl‐3‐aminoisoxazole ,and the structure was characterized by 1 H NMR ,13 C NMR and elemental analysis .The factors affecting the yield of target product was investigated ,and an optimized synthetic condition was obtained .
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