Research progress on mechanism of curcumin in treatment of the urinary and reproductive system cancers
Author(s): HAN Wei, LEI Yong-sheng, Dispensary of Traditional Chinese Medicine, Tianjin Jinghai District Hospital, Tianjin Institute of Pharmaceutical Research
Pages: 260-264
Year: 2016 Issue: 2
Journal: World Phytomedicines
Keyword: curcumin; bladder carcinoma; renal carcinoma; prostate carcinoma; cervical carcinoma; ovarian carcinoma;
Abstract: Curcumin is the main active component of Curcuma longa L., and has been used in treatment of various diseases. Studies have indicated that curcumin has protective effects on multiple organ systems. The molecular mechanism is achieved by inhibiting the signal transduction pathway of multiple levels of cells. Curcumin can inhibit the cell’s activity directly or indirectly by the formation of the target molecules. These target molecules include transcription factors, growth factors, enzymes, proteins, enzymes, active cells, serum, and resistance proteins. In this paper, the effects of curcumin on the cancer of the urinary and reproductive systems, and their molecular pathways, which provide a reference for more extensive application in treatment of various carcinomas.
Pages: 260-264
Year: 2016 Issue: 2
Journal: World Phytomedicines
Keyword: curcumin; bladder carcinoma; renal carcinoma; prostate carcinoma; cervical carcinoma; ovarian carcinoma;
Abstract: Curcumin is the main active component of Curcuma longa L., and has been used in treatment of various diseases. Studies have indicated that curcumin has protective effects on multiple organ systems. The molecular mechanism is achieved by inhibiting the signal transduction pathway of multiple levels of cells. Curcumin can inhibit the cell’s activity directly or indirectly by the formation of the target molecules. These target molecules include transcription factors, growth factors, enzymes, proteins, enzymes, active cells, serum, and resistance proteins. In this paper, the effects of curcumin on the cancer of the urinary and reproductive systems, and their molecular pathways, which provide a reference for more extensive application in treatment of various carcinomas.
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