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Preparation technique of drug-loaded microsphere by using poly lactic-co-glycolic acid
Author(s): 
Pages: 92-97
Year: Issue:  1
Journal: Chinese Journal of Medical Physics

Keyword:  poly lactic-co-glycolic aciddrug-loaded microspherepreparationreview;
Abstract: As a well biocompatible and biodegradable polymer, poly lactic-co-glycolic acid(PLGA) is very important in the biomedical field. The measures for preparing microsphere by using PLGA includes emulsion- solvent evaporation, phase separation, salting-out method, spray drying method, membrane emulsification, nanoprecipitation, supercritical fluid technology and so on. The principle, advantage and disadvantage, and research progress of mentioned techniques were summarized by analyzing domestic and foreign literatures.
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