Author(s): ZHANG Li-hua, LI Ke, BU Fang-fang, Department of Pharmacy, Zhongnan Hospital of Wuhan University, International Education College, Hubei University of Chinese Medicine, Department of Pharmacy, Hubei Hospital of Traditional Chinese Medicine
Pages: 52-56
Year: 2016 Issue:  1
Journal: Central South Pharmacy
Keyword:  sodium alginate; drug delivery system; microsphere; nanoparticle; floating system;
Abstract: Sodium alginate is a natural polysaccharide polymer isolated from seaweeds or algae, which is an anionic linear polysaccharide composed of(1→4)-β-D-mannuronic acid and(1→4)-α-L-guluronic acid. Being biocompatible and biodegradable, nontoxic and easily available, it is widely used in microspheres, nanoparticles, pellets, matrix tablets, floating systems and liposome drug delivery system. This review presented the latest research of sodium alginate in the past few years and the trends of sodium alginate in the pharmaceutic preparation.