Effect Analysis of Jiawei Yigong Powder in Treating of Diabetes Gastroparesis
Author(s): ZHANG Yu-feng, LIU Xin-ai, YE Kun-ying, GAO Xi-yan, Henan College of Traditional Chinese Medicine
Pages: 164-167
Year: 2016 Issue: 2
Journal: Chinese Journal of Experimental Traditional Medical Formulae
Keyword: diabetic gastroparesis; jiawei Yigong powder; gastric emptying; gastrin; motilin;
Abstract: Objective: To discuss the curative effect of Jiawei Yigong powder in treating diabetes gastroparesis(DGP) and its influence on plasma motilin and gastrin. Method: Ninety four patients were randomly divided into control group(46 cases) and observation group(48 cases). Patients in control group took mosapride citrate tablets,5 mg / time,3 times / day,at 30 min before meal; Sulfur acid capsules,0. 6 g / time,1time / day,at 30 min before breakfast. Besides the therapy of control group,patients in observation group were additionally treated with Jiawei Yigong powder,1 dose / day. The treatment course of both groups lasted for 4weeks. Efforts were made to detect gastric emptying by B ultrasonic before and after treatment,record gastric half emptying time(T1/2),gastric emptying time(T),score the symptom severity index(GCSI) of the stomach and mild paralysis,and test the levels of plasma motilin and gastrin before and after treatment. Result: Total effective rate in observation group was 91. 8%,which was superior to 74. 4% in control group(P < 0. 05). After treatment,gastric half emptying time and gastric emptying time in observation group were shorter than these in control group(P < 0. 05). Postprandial abdominal distension /early full,nausea and vomiting,abdominal distension score and gastroparesis total score in observation group were all lower than these data in control group(P < 0. 01). Levels of motilin and gastrin in observation group were lower than the standards in control group(P < 0. 01). Conclusion:Oral administration of Jiawei Yigong powder can reduce clinical symptoms of DGP patients,regulate gastrointestinal hormone,promote the gastric emptying,improve the clinical curative effect,and so is worth further studies.
Pages: 164-167
Year: 2016 Issue: 2
Journal: Chinese Journal of Experimental Traditional Medical Formulae
Keyword: diabetic gastroparesis; jiawei Yigong powder; gastric emptying; gastrin; motilin;
Abstract: Objective: To discuss the curative effect of Jiawei Yigong powder in treating diabetes gastroparesis(DGP) and its influence on plasma motilin and gastrin. Method: Ninety four patients were randomly divided into control group(46 cases) and observation group(48 cases). Patients in control group took mosapride citrate tablets,5 mg / time,3 times / day,at 30 min before meal; Sulfur acid capsules,0. 6 g / time,1time / day,at 30 min before breakfast. Besides the therapy of control group,patients in observation group were additionally treated with Jiawei Yigong powder,1 dose / day. The treatment course of both groups lasted for 4weeks. Efforts were made to detect gastric emptying by B ultrasonic before and after treatment,record gastric half emptying time(T1/2),gastric emptying time(T),score the symptom severity index(GCSI) of the stomach and mild paralysis,and test the levels of plasma motilin and gastrin before and after treatment. Result: Total effective rate in observation group was 91. 8%,which was superior to 74. 4% in control group(P < 0. 05). After treatment,gastric half emptying time and gastric emptying time in observation group were shorter than these in control group(P < 0. 05). Postprandial abdominal distension /early full,nausea and vomiting,abdominal distension score and gastroparesis total score in observation group were all lower than these data in control group(P < 0. 01). Levels of motilin and gastrin in observation group were lower than the standards in control group(P < 0. 01). Conclusion:Oral administration of Jiawei Yigong powder can reduce clinical symptoms of DGP patients,regulate gastrointestinal hormone,promote the gastric emptying,improve the clinical curative effect,and so is worth further studies.
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