Clinical analysis of ovarian malignancies in 139 young female patients
Author(s): XU Xiaofei, WANG Hui, ZHANG Wenke, YAO Yuanqing, Department of Obstetrics and Gynecology, Chinese PLA General Hospital
Pages: 18-20
Year: 2016 Issue: 1
Journal: Chinese Journal of Clinical Obstetrics and Gynecology
Keyword: ovarian malignant tumor; young women; fertility-sparing surgery;
Abstract: Objective To analysis the characteristics and optimal treatments of ovarian malignancies in young women aged less than 30 years.Methods Retrospective analysis was performed for the clinical data of ovarian malignancies in young women aged less than 30 years who were treated in Chinese PLA General Hospital from January2010 to January 2015.Results 87.77%(122/139)patients have obvious clinical symptoms.Ovarian malignant tumor pathologic classification including 58 epithelial tumors,79 germ cell tumors,1sex cord stromal tumor and 1metastatic ovarian tumor.Surgical pathology staging:103cases in stageⅠ,13inⅡ,18inⅢand 5in stageⅣ.109 cases underwent preserving fertility function surgery.127 cases took postoperative adjuvant chemotherapy.Among those whose follow-up time more than 24 months,8cases recurred,65 cases were disease-free and 5dead.66 patients had normal menstruation period after chemotherapy,33 of them had fertility desire and 21 pregnancies achieved with 11full-term birth.Conclusions Germ cell tumor was the most common ovarian malignancies in young women under 30 years old.Early clinical surgical pathological staging ovarian malignant tumor can best be treated with conservative surgery,followed by adjuvant chemotherapy.
Pages: 18-20
Year: 2016 Issue: 1
Journal: Chinese Journal of Clinical Obstetrics and Gynecology
Keyword: ovarian malignant tumor; young women; fertility-sparing surgery;
Abstract: Objective To analysis the characteristics and optimal treatments of ovarian malignancies in young women aged less than 30 years.Methods Retrospective analysis was performed for the clinical data of ovarian malignancies in young women aged less than 30 years who were treated in Chinese PLA General Hospital from January2010 to January 2015.Results 87.77%(122/139)patients have obvious clinical symptoms.Ovarian malignant tumor pathologic classification including 58 epithelial tumors,79 germ cell tumors,1sex cord stromal tumor and 1metastatic ovarian tumor.Surgical pathology staging:103cases in stageⅠ,13inⅡ,18inⅢand 5in stageⅣ.109 cases underwent preserving fertility function surgery.127 cases took postoperative adjuvant chemotherapy.Among those whose follow-up time more than 24 months,8cases recurred,65 cases were disease-free and 5dead.66 patients had normal menstruation period after chemotherapy,33 of them had fertility desire and 21 pregnancies achieved with 11full-term birth.Conclusions Germ cell tumor was the most common ovarian malignancies in young women under 30 years old.Early clinical surgical pathological staging ovarian malignant tumor can best be treated with conservative surgery,followed by adjuvant chemotherapy.
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