Synthesis and spectral characterizations of (O,O)-dialkyl-α-phenyl-α-(4-substituted benzoylamino) methylphosphonate
Author(s): FANG Hua, CHEN Weizhu, ZHANG Yiping, YI Ruizao, HONG Zhuan
Pages: 590-596,600
Year: 2015 Issue: 6
Journal: Chemical Research
Keyword: phosphonate; spectral characterization; MS fragmentation pathways; crystal struc-ture;
Abstract: A series of (O ,O)‐dialkyl‐α‐phenyl‐α‐(4‐substituted benzoylamino) methylphospho‐nate were synthesized from α‐aminophosphonate and 4‐substituted benzoic acid chloride under ice bath .The products were characterized by elemental analysis ,IR ,NMR (1 H NMR ,13 C NMR and 31 P NMR) and mass spectrometry .In order to further confirmed the structure of these compounds ,4f ,4g ,4i ,4j ,4k and 4l were determined by X‐ray diffractometer .The proto‐nated molecules [M + H ]+ of compounds 4a - 4f were analyzed under electrospray ionization tandem mass spectrometric conditions ,at the same time ,attempts were made to explain the possible mechanism of the formation of rearrangement ion .
Pages: 590-596,600
Year: 2015 Issue: 6
Journal: Chemical Research
Keyword: phosphonate; spectral characterization; MS fragmentation pathways; crystal struc-ture;
Abstract: A series of (O ,O)‐dialkyl‐α‐phenyl‐α‐(4‐substituted benzoylamino) methylphospho‐nate were synthesized from α‐aminophosphonate and 4‐substituted benzoic acid chloride under ice bath .The products were characterized by elemental analysis ,IR ,NMR (1 H NMR ,13 C NMR and 31 P NMR) and mass spectrometry .In order to further confirmed the structure of these compounds ,4f ,4g ,4i ,4j ,4k and 4l were determined by X‐ray diffractometer .The proto‐nated molecules [M + H ]+ of compounds 4a - 4f were analyzed under electrospray ionization tandem mass spectrometric conditions ,at the same time ,attempts were made to explain the possible mechanism of the formation of rearrangement ion .
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