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Research Progress of Micro RNA-193b and Obesity
Pages: 2130-2135
Year: Issue:  10
Journal: World Science and Technology-Modernization of Traditional Chinese Medicine

Keyword:  Micro RNAmi RNA-193badipocyte differentiationobesity;
Abstract: Micro RNAs(mi RNAs) were found as a species of small non-coding single-stranded RNA molecules with the size of 20 to 25 nucleotides in recent years, which featured highly conserved and endogeny. It depredated and inhibited the target m RNA translation by complementary base pairing with the target m RNA. According to the latest study, mi RNA was closely related with obesity, type 2 diabetes and other metabolic diseases. Obesity had became a major public health problem worldwide, which showed as an unusual increase in both the number and size of fat cells based on excessive accumulation of fat lead by the body’s energy metabolism imbalance of a metabolic disease. Among them, mi RNA-193b-365 had an abnormal expression in adipocyte differentiation and obesity status. It might be involved in adipocyte differentiation and the development of obesity. Thus, it was of great significance to do a deep research in the understanding adipocyte differentiation mechanism to prevent and treat obesity. This paper reviewed research progress in this field.
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