An analysis of the distribution of the pathogenic bacteria causing orofacial space infections in 377 patients and the drug resistance of those bacteria
Author(s): YANG Jing, LI Yong-sheng, ZOU Hong-ju, The Department of Oral and Maxillofacial Surgery, The First People’s Hospital of Yunnan Province
Pages: 936-939
Year: 2015 Issue: 10
Journal: Journal of Pathogen Biology
Keyword: Orofacial space infections; pathogenic bacteria; drug sensitivity test; drug resistance;
Abstract: Objectives To investigate the distribution and drug resistance of pathogenic bacteria causing an infection extending to the potential fascial spaces in the orofacial area(orofacial space infections)in order to provide a reference for reducing nosocomial infections. Methods Cases of orofacial space infections were compiled,and pus samples were collected from patients and cultured.The drug sensitivity of pathogenic bacteria was determined using the disc diffusion method,and the data were analyzed using software for statistical analysis. Results A total of 352 strains of pathogens were isolated from 377 patients with orofacial space infections.These strains included 201 strains of Gram-positive bacteria,146 strains of Gram-negative bacteria,and 5strains of fungi.Most of the strains of Gram-positive bacteria detected were Staphylococcus aureus or S.hemolyticus,followed by S.epidermidis and S.pneumoniae.The most prevalent strains of Gram-negative bacteria were Klebsiella pneumoniae(20.74%),followed by Pseudomonas aeruginosaand Escherichia coli.The only strain of fungus detected was Candida albicans.The 201 strains of Gram-positive bacteria were subjected to drug susceptibility testing,and results revealed that all of the bacteria except for S.pneumoniae were susceptible to Macrodantin.The Gram-positive bacteria all had varying degrees of resistance to Trimesulf,ciprofloxacin,rifampicin,gentamycin,Macrodantin,tetracycline,chlorine lincomycin,erythromycin,and chloramphenicol.The 146 strains of Gram-negative bacteria were subjected to drug susceptibility testing,and results revealed that the Gram-negative bacteria all had varying degrees of resistance to Trimesulf,gentamycin,ciprofloxacin,tobramycin,imipenem,aztreonam,Macrodantin,and ampicillin.E.coli was completely resistant to ampicillin. Conclusion A wide variety of pathogens caused orofacial space infections and these pathogens had serious drug resistance.During clinical treatment,drugs should be used rationally to control the development of further drug resistance.
Pages: 936-939
Year: 2015 Issue: 10
Journal: Journal of Pathogen Biology
Keyword: Orofacial space infections; pathogenic bacteria; drug sensitivity test; drug resistance;
Abstract: Objectives To investigate the distribution and drug resistance of pathogenic bacteria causing an infection extending to the potential fascial spaces in the orofacial area(orofacial space infections)in order to provide a reference for reducing nosocomial infections. Methods Cases of orofacial space infections were compiled,and pus samples were collected from patients and cultured.The drug sensitivity of pathogenic bacteria was determined using the disc diffusion method,and the data were analyzed using software for statistical analysis. Results A total of 352 strains of pathogens were isolated from 377 patients with orofacial space infections.These strains included 201 strains of Gram-positive bacteria,146 strains of Gram-negative bacteria,and 5strains of fungi.Most of the strains of Gram-positive bacteria detected were Staphylococcus aureus or S.hemolyticus,followed by S.epidermidis and S.pneumoniae.The most prevalent strains of Gram-negative bacteria were Klebsiella pneumoniae(20.74%),followed by Pseudomonas aeruginosaand Escherichia coli.The only strain of fungus detected was Candida albicans.The 201 strains of Gram-positive bacteria were subjected to drug susceptibility testing,and results revealed that all of the bacteria except for S.pneumoniae were susceptible to Macrodantin.The Gram-positive bacteria all had varying degrees of resistance to Trimesulf,ciprofloxacin,rifampicin,gentamycin,Macrodantin,tetracycline,chlorine lincomycin,erythromycin,and chloramphenicol.The 146 strains of Gram-negative bacteria were subjected to drug susceptibility testing,and results revealed that the Gram-negative bacteria all had varying degrees of resistance to Trimesulf,gentamycin,ciprofloxacin,tobramycin,imipenem,aztreonam,Macrodantin,and ampicillin.E.coli was completely resistant to ampicillin. Conclusion A wide variety of pathogens caused orofacial space infections and these pathogens had serious drug resistance.During clinical treatment,drugs should be used rationally to control the development of further drug resistance.
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