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Clinical observation of Yixinshu Capsules combined with amiodarone in treatment of ventricular premature beat
Author(s): 
Pages: 1460-1463
Year: Issue:  12
Journal: World Phytomedicines

Keyword:  Yixinshu CapsulesAmiodarone Hydrochloride Tabletsventricular premature beatsymptom scores;
Abstract: Objective To observe the clinical effect of Yixinshu Capsules combined with amiodarone in treatment of ventricular premature beat. Methods Patients(104 cases) with premature ventricular were enrolled in this study from June 2014 to January 2015. According to the different treatment plan, patients were divided into treatment group(56 cases) and control group(48 cases). The patients in the control group were po administered with Amiodarone Hydrochloride Tablets, 0.2 g/time, three times daily in the first week, twice daily in the second week, once daily in the third and fourth week. The patients in the treatment group were po administered with Yixinshu Capsules on the basis of control group, 3 grains/time, three times daily. The patients in two groups were treated for 4 weeks. After treatment, the clinical efficacy, ventricular premature beat efficacies, and electrocardiogram efficacies were evaluated; And the changes of clinical symptom scores in two groups before and after treatment were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 96.43%, respectively, and ventricular premature beat efficacies in two groups were 72.92% and 89.29%, electrocardiogram efficacies in two groups were 77.08% and 91.07%, and there were differences between two groups(P < 0.05). The symptom scores of heart palpitations, weakness, shortness of breath, and chest tightness of chest pain in two groups were significantly reduced; And the difference was statistically significant in the same group(P < 0.05). These observational indexes in the treatment group were better than those in the control group, with significant differences between two groups(P < 0.05). Conclusion Yixinshu Capsules combined with amiodarone has clinical curative effect in treatment of ventricular premature beat, and can significantly improve the clinical symptoms with less adverse reaction, which has a certain clinical application value.
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