Clinical observation of Vitamin A and D Drops combined with montelukast sodium in treatment of capillary bronchitis
Author(s): ZHANG Gui-ping, FU Huan-qiao, ZHANG Wen-yan, Department of Pediatrics, Maternity and Child Health Hospital of Hengshui City Taocheng District
Pages: 1494-1497
Year: 2015 Issue: 12
Journal: World Phytomedicines
Keyword: Vitamin A and D Drops; Montelukast Sodium Chewable Tablets; capillary bronchitis;
Abstract: Objective To observe the clinical efficacy of Vitamin A and D Drops combined with Montelukast Sodium Chewable Tablets in treatment of capillary bronchitis. Methods Children(80 cases) with capillary bronchitis in Maternity and Child Health Hospital of Hengshui City Taocheng District from January 2015 to June 2015 were randomly divided into control and treatment groups, and each group had 40 cases. Children in control group were po administered with Montelukast Sodium Chewable Tablets, once daily at night. The amounts of drugs were corresponding with ages of children, such as below six months children had 2 mg/ time, but above six months children had 4 mg/ time. Children in treatment group were added Vitamin A and D Drops on the basis of control group, 1 grain/time, once daily. The children in two groups were treated for 7 d. The clinical efficacies and symptoms of the two groups were observed, and the levels of γ-interferon(IFN-γ), immunoglobulin A(Ig A), immunoglobulin G(Ig G), and immunoglobulin M(Ig M) were compared between two groups. Results After treatment, the efficacies in the control and treatment groups were 87.5% and 95.0%, respectively, and there were significant differences between two groups(P < 0.05). After treatment, disappear time of breath, cough, wheezing, and pulmonary symptoms, and returned to normal time of respiration and heart rate in treatment group were significantly shorter than those in the control group, with significant difference between two groups(P < 0.05). After treatment, level of IFN-γ was obviously increased, and the difference was statistically significant in the same group(P < 0.05). The observational index in the treatment group was better than that in the control group, with significant difference between two groups(P < 0.05). Conclusion Vitamin A and D Drops combined with Montelukast Sodium Chewable Tablets has clinical curative effect in treatment of capillary bronchitis, can significantly reduce the clinical symptoms and signs, and less adverse reactions, which has a certain clinical application value.
Pages: 1494-1497
Year: 2015 Issue: 12
Journal: World Phytomedicines
Keyword: Vitamin A and D Drops; Montelukast Sodium Chewable Tablets; capillary bronchitis;
Abstract: Objective To observe the clinical efficacy of Vitamin A and D Drops combined with Montelukast Sodium Chewable Tablets in treatment of capillary bronchitis. Methods Children(80 cases) with capillary bronchitis in Maternity and Child Health Hospital of Hengshui City Taocheng District from January 2015 to June 2015 were randomly divided into control and treatment groups, and each group had 40 cases. Children in control group were po administered with Montelukast Sodium Chewable Tablets, once daily at night. The amounts of drugs were corresponding with ages of children, such as below six months children had 2 mg/ time, but above six months children had 4 mg/ time. Children in treatment group were added Vitamin A and D Drops on the basis of control group, 1 grain/time, once daily. The children in two groups were treated for 7 d. The clinical efficacies and symptoms of the two groups were observed, and the levels of γ-interferon(IFN-γ), immunoglobulin A(Ig A), immunoglobulin G(Ig G), and immunoglobulin M(Ig M) were compared between two groups. Results After treatment, the efficacies in the control and treatment groups were 87.5% and 95.0%, respectively, and there were significant differences between two groups(P < 0.05). After treatment, disappear time of breath, cough, wheezing, and pulmonary symptoms, and returned to normal time of respiration and heart rate in treatment group were significantly shorter than those in the control group, with significant difference between two groups(P < 0.05). After treatment, level of IFN-γ was obviously increased, and the difference was statistically significant in the same group(P < 0.05). The observational index in the treatment group was better than that in the control group, with significant difference between two groups(P < 0.05). Conclusion Vitamin A and D Drops combined with Montelukast Sodium Chewable Tablets has clinical curative effect in treatment of capillary bronchitis, can significantly reduce the clinical symptoms and signs, and less adverse reactions, which has a certain clinical application value.
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