The server is under maintenance between 08:00 to 12:00 (GMT+08:00), and please visit later.
We apologize for any inconvenience caused
Login  | Sign Up  |  Oriprobe Inc. Feed
China/Asia On Demand
Journal Articles
Laws/Policies/Regulations
Companies/Products
Bookmark and Share
Clinical observation of Mingmu Dihuang Pills combined with compound anisodine in treatment of optic atrophy
Author(s): 
Pages: 1524-1527
Year: Issue:  12
Journal: World Phytomedicines

Keyword:  Mingmu Dihuang PillsCompound Anisodine Hydrobromide Injectionoptic atrophyvisual field defectP100 wave incubation period;
Abstract: Objective To observe the clinical effect of Mingmu Dihuang Pills combined with compound anisodine in treatment of optic atrophy. Methods Patients(88 cases) with optic atrophy in Department of Ophthalmology of Xi’an Hospital of Traditional Chinese Medicine from June 2014 to June 2015 were enrolled in this study. According to the different treatment plan, patients were divided into treatment group(44 cases) and control group(44 cases). The patients in the control group were sc administered with Compound Anisodine Hydrobromide Injection, 2 m L/time, once daily. The patients in the treatment group were po administered with Mingmu Dihuang Pills on the basis of control group, 1 pill/time, twice daily. Two weeks was as one course, and the patients in two groups were treated for three courses. Each course had a five-day interval. After treatment, the clinical efficacy were evaluated, and the changes of visual field defect, P100 wave incubation period, the lines number of eyesight improve in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 75.00% and 90.91%, respectively, and there were differences between two groups(P < 0.05). After treatment, visual field defect and P100 wave incubation period in two groups were significantly decreased, and the difference was statistically significant in the same group(P < 0.05). After treatment, the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups(P < 0.05). The line numbers of eyesight improve in treatment group was better than that of control group, with significant difference between two groups(P < 0.05). The incidence of adverse reactions in the control and treatment groups were 2.27% and 4.55%, respectively, and there were no differences between two groups. Conclusion Mingmu Dihuang Pills combined with compound anisodine has distinct clinical effect in treatment of optic atrophy, and can promote the patients’ visual acuity, also can reduce visual field defect, which has a certain clinical application value.
Related Articles
No related articles found