Author(s): Wu Xuan, Chen Kaitian, Zhuang Huiwen, Chen Xihui
Pages: 3110-3112
Year: 2015 Issue:  21
Journal: International Medicine & Health Guidance News
Keyword:  Tympanoplasty; Mycosis; Therapy;
Abstract: Objective To analyze the clinical features and different treatment methods of fungal infection in surgical cavity after canal wall down tympanoplasty.Methods The clinical characteristics and fugal flora distribution of 45 patients (45 ears) with fungal infection in surgical mastoid cavity enrolled from January, 2013 to November, 2014 were analyzed.The fungal infectious lesion in surgical cavity was cleared under otoendoscope.Then, the patients were divided into a boric acid alcohol group (20 ears) and a pevisone cream group (25 ears).The treatment efficacies were compared between these two groups.Results Fugal cultures mainly found aspergillus.Most the patients complicated with bacteria infection.4 weeks after the treatment, 22 ears were cured, 3 responsed well, none didn't response, the total efficacy was 100％, and 4 (16％) re-occurred half year from then in the pevisone cream group and 9 were cured, 6 responsed well, 5 didn't responsed, the total efficacy was 75％, and 12 (60％) re-occurred half year from then in the boric acid alcohol group.There were statistical differences in total efficacy and recurrence rate between these two groups.Conclusions Fungal infection commonly occurs after canal wall down tympanoplasty.Otoendoscopic treatment combined pevisone cream is better than with boric acid alcohol and has a lower recurrence rate.