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Genetic polymorphism of the STR DXS9898 locus in Han population
Author(s): HUANG Daixin, LIANG Weibo, WU Meizuo, ZHANG Lin
Pages: 150-
151,154
Year: 2002
Issue:
3
Journal: JOURNAL OF FORENSIC MEDICINE
Keyword: 短串联重复序列; DXS9898; 聚合酶链反应; 多态性;
Abstract: 目的研究汉族群体DXS9898基因座的遗传多态性,为法科学应用提供基础数据.方法应用PCR及PAG电泳技术,对成都地区汉族群体199名女性无关个体及97名男性无关个体进行群体遗传学调查.结果共检出6个等位基因,片段大小为189~214bp,其基因型分布符合Hardy-Weinberg平衡.家系调查证实等位基因的传递遵循孟德尔遗传规律.女性样本杂合度为0.593 0;男、女性样本个人识别能力(Dp)分别为0.566 7、0.9420;父-母-女三联体鉴定的非父排除率(PE)为0.5862.结论DXS9898基因座在法科学个人识别及女性小孩的亲权鉴定中具有较高的实用价值.
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