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Clinical Observation on Shexiang Baoxin Pill in the Treatment of Chronic Heart Failure Induced by Coronary Heart Disease
Pages: 1704-1706
Year: Issue:  15
Journal: Research of Traditional Chinese Medicine

Keyword:  chronic heart failureShexiang Baoxin pillcoronary heart disease;
Abstract: Objective To investigate the efficacy of Shexiang Baoxin pill(SBP)in treating chronic heart failure(CHF)induced by coronary heart disease(CHD).Methods One hundred patients with CHF induced by CHD were randomly divided into two groups:The control group(n=50)treated with routine treatment,and the treatment group(n=50)treated with routine treatment plus SBP for 6weeks.The cardiac function,plasma N-terminal pro-brain-type natriuretic peptide(NT-proBNP)and serum heart-fatty acid-binding protein(H-FABP)levels were observed.Results After treatment,left ventricular(LV)ejection fraction(LVEF),LV end diastolic diameter(LVEDD),LV end-systolic diameter(LVESD),cardiac output(CO),SV and 6 min walking distance were improved in two groups,the degree of improvement in treatment group was better than that in control group(P<0.05).The levels of plasma NTproBNP and serum H-FABP in treatment group was lower than that in control group(P<0.05).The clinical efficacy in treatment group was better than that in control group(P<0.05).Conclusion SBP can improve the cardiac function,reduce the levels of plasma NT-proBNP and serum H-FABP in patients with CHF induced by CHD.
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