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can zuo zhu she ye dui bu wen ding xing xin jiao tong huan zhe pai-1 biao da de ying xiang
Author(s): 
Pages: 1754-1755
Year: Issue:  15
Journal: Research of Traditional Chinese Medicine

Keyword:  不稳定型心绞痛参芎注射液血浆纤溶酶原激活物抑制剂-1;
Abstract: 目的研究参芎注射液对不稳定型心绞痛患者纤溶酶原激活物抑制剂-1(PAI-1)表达的影响。方法入选164例患者随机分为两组,即对照组和干预组。检测所有入选患者入院时的PAI-1含量,对照组给予不稳定型心绞痛标准治疗,干预组在不稳定型心绞痛标准治疗基础上,加用参芎注射液治疗。两组患者治疗2周后复查PAI-1含量。结果两组入院时PAI-1的血清含量比较,差异无统计学意义(t=1.40,P>0.05);治疗2周后两组复查PAI-1的血清含量比较,差异有统计学意义(t=2.69,P<0.05)。结论参芎注射液可降低不稳定型心绞痛患者急性期血清PAI-1的分子含量,但是对于冠心病患者长期疗效还需要深入研究。
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