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Issue:
Aging and epigenetics
Author(s):
WANG Ben
,
XIE Hong-fu
,
LI Ji
Pages:
593
-
596
Year:
2015
Issue:
9
Journal:
Journal of Clinical Dermatology
Keyword:
衰老
;
表观遗传学
;
DNA甲基化
;
组蛋白修饰
;
非编码RNA
;
Abstract:
过去的20余年间,人类长寿及衰老领域的研究层出不穷,成为生命科学研究领域的一大热点。表观遗传学的研究在衰老领域更是从未间断,这是一个复杂的调控网络。该文从DNA甲基化、组蛋白修饰、染色质重塑、非编码RNA调控等多方面阐释表观遗传学机制在衰老发生及发展过程中的调控,以期为将来衰老机制及抗衰老研究提供更全面的基础理论依据。
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