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Two different dose calculation algorithms in intensity-modulated radiotherapy planning
Author(s): 
Pages: 401-403
Year: Issue:  3
Journal: Chinese Journal of Medical Physics

Keyword:  intensity modulated radiotherapyfastsuperposition algorithmFFT convolution algorithm;
Abstract: Objective The results of two different dose calculation algorithms in Xio treatment planning system were compared to instruct the clinical application. Methods Seven NPC patients were randomly selected. For these patients, the treatment plans were calculated by Fastsuperposition. Based on these plans, new plans were calculated by FFT convolution, while keeping all the setting conditions unchanged. Comparison was made between the two plans including the dose distribution, the dose volume histogram, the time of optimizations, the time of treatment and number of monitor unit(MU), but were play by pairing-t test. Results Compared with the FFT convolution algorithm, PTVnx95% coverage of Fastsuperposition became lower(t=- 4.178, P=0.006). HI became worse(t=- 1.374, P=0.219). CI increased(t=0.942, P=0.382); PTV195% coverage of Fastsuperposition became lower(t=- 4.530, P=0.004). HI have no difference(t=- 0.079, P=0.940). CI became worse(t=-1.679, P=0.144); PTV295% coverage of Fastsuperposition became lower(t=- 4.130, P=0.006), HI increased(t=2.264, P=0.064), CI became worse(t=-2.819, P=0.030); D30 of the right parotid was reduced(t=-0.539, P=0.609); D30 of the left parotid was reduced(t=-1.236, P=0.263); D1 cm3 of spine was reduced(t=0.622,P=0.557); Dmaxof brainstem was reduced(t=-1.306, P=0.239); the monitor unit of machine was decreased(t=-4.790, P=0.000); Gamma passing rate became increased(t=-0.601, P=0.560). Conclusion In comparison with FFT convolution algorithm, Fastsuperposition algorithm reduce the dose of organs at risk, shorten the time of optimization.
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