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Issue:
Investigation on Synthesizing Mebendazole of c- Polymorphic
Author(s):
LIU Xiangyi
,
ZHU Jianmin
Pages:
35
-
37
Year:
2002
Issue:
3
Journal:
JIANGSU CHEMICAL INDUSTRY
Keyword:
对氯苯甲酸
;
3-硝基-4-氯-苯甲酸
;
4-氯-3-硝基二苯甲酮
;
4-氨基-3硝基二苯甲酮
;
3
;
4-二氨基二苯甲酮
;
C-型甲苯咪唑
;
Abstract:
以对氯苯甲酸为起始原料,经硝化、氯化、酮化、氨解、还原、环合、转晶7步反应完成C型甲苯咪唑的制备,总收率以对氯苯甲酸计约63.8%.
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