Research of cognitive function and influencing factors in first-degree relatives of elderly schizophrenia
Author(s): Jiang Guoqing, Li Yuan, Wen Yan, Zhao Ke, Huang Jie, Cao Guoxing, Zhang Daij iang, Jiang Pingj ing, Cheng Xue, Tan Xiaolin
Pages: 3457-3459
Year: 2015 Issue: 25
Journal: Chongqing Medical Journal
Keyword: geriatric psychiatry; first-degree relatives; cognitive;
Abstract: Objective To investigate the cognitive function and its influencing factors in first-degree relatives of elderly schiz-ophrenia.Methods Totally 30 cases of healthy children with elderly patients with schizophrenia(a family group ),50 cases of pa-tients with schizophrenia(patient group),52 healthy elderly subjects (health group)all accepeted mini-mental state examination (MMSE),clinical memory scale(CMS),wisconsin card sorting test(WCST),trail making test(TMT-A),number sign(DSy)and digit span(DSp)tests.The influencing factors were analyzed by stepwise multiple regression analysis method.Results The MMSE score,MQ,connection time,DSy points,and DSp scores of kinship group were significantly higher in patients group(P <0.05).The accomplishments of its WCST of patient group was with no significant difference(P >0.05),and its completed categories,connec-tion time was significantly lower than the normal group (P < 0.05 ).Years of education and BEAM were incorporated into the MMSE,the number of sustained response were the dependent variable regression equation,the coefficient of determination R 2 was 0.276 and 0.422,Life events,BEAM,personality,parent-child relationship,previous occupation MQ were the dependent variable in-to the regression equation,R 2 was 0.475.Years of education and MMSE score,MQ were significant positive correlation(P <0.05), and sustained response were significantly negatively correlated(P <0.01);BEAM and sustained response were significantly correla-ted(P <0.01);age and completed categories were significantly negatively correlated and the connection time is significant positive correlation(P <0.05);life events,parent-child relationship were significant negative correlation with MQ(P <0.05).Conclusion First-degree relatives of elderly schizophrenia have obvious executive dysfunction,the impact of factors including years of education, BEAM and age.
Pages: 3457-3459
Year: 2015 Issue: 25
Journal: Chongqing Medical Journal
Keyword: geriatric psychiatry; first-degree relatives; cognitive;
Abstract: Objective To investigate the cognitive function and its influencing factors in first-degree relatives of elderly schiz-ophrenia.Methods Totally 30 cases of healthy children with elderly patients with schizophrenia(a family group ),50 cases of pa-tients with schizophrenia(patient group),52 healthy elderly subjects (health group)all accepeted mini-mental state examination (MMSE),clinical memory scale(CMS),wisconsin card sorting test(WCST),trail making test(TMT-A),number sign(DSy)and digit span(DSp)tests.The influencing factors were analyzed by stepwise multiple regression analysis method.Results The MMSE score,MQ,connection time,DSy points,and DSp scores of kinship group were significantly higher in patients group(P <0.05).The accomplishments of its WCST of patient group was with no significant difference(P >0.05),and its completed categories,connec-tion time was significantly lower than the normal group (P < 0.05 ).Years of education and BEAM were incorporated into the MMSE,the number of sustained response were the dependent variable regression equation,the coefficient of determination R 2 was 0.276 and 0.422,Life events,BEAM,personality,parent-child relationship,previous occupation MQ were the dependent variable in-to the regression equation,R 2 was 0.475.Years of education and MMSE score,MQ were significant positive correlation(P <0.05), and sustained response were significantly negatively correlated(P <0.01);BEAM and sustained response were significantly correla-ted(P <0.01);age and completed categories were significantly negatively correlated and the connection time is significant positive correlation(P <0.05);life events,parent-child relationship were significant negative correlation with MQ(P <0.05).Conclusion First-degree relatives of elderly schizophrenia have obvious executive dysfunction,the impact of factors including years of education, BEAM and age.
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