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Spectral CT imaging in differential diagnosis of hepatic cyst and unilocular hepatic cystic echinococcosis
Author(s): 
Pages: 1344-1348
Year: Issue:  9
Journal: Chinese Journal of Medical Imaging Technology

Keyword:  LiverEchinococcosisTomographyX-ray conputedGemstone spectral imaging;
Abstract: Objective To investigate the value of spectral CT imaging in differential diagnosis of hepatic cyst(HC)and unilocular hepatic cystic echinococcosis(UHCE).Methods Thirty-nine patients with 19 HC and 20 UHCE were enrolled.All the patients underwent plain CT and tri-phase enhanced CT with single-source dual-energy mode.Material decomposition images and monochromatic images(40—140keV)were reconstructed.The iodine concentration(IC),water concentration(WC)and the effective-Z were measured for lesions,normal liver parenchyma and aorta in each phase.The normalized iodine concentration(NIC)and lesion-to-normal parenchyma iodine concentration ratio(LNR)were calculated.Statistical and ROC analysis were performed.Results The mean CT values of monochoromatic energy with 40 keV and 50 keV in HC were significantly lower than those in UHCE during the plain,arterial and venous phase.The IC during all scan phases and effective-Z values during plain,arterial and venous phase were significantly lower than those in UHCE(all P<0.05).The NIC of HC were significantly higher than that of UHCE during the plain,arterial phases(both P<0.05).The mean WC of HC during arterial phase were lower than that of UHCE(P<0.05).Identification of HC and UHCE in plain40 keV had highest sensitivity(100%)and specificity(75%).Conclusion Quantitative analysis of spectral CT imaging has been a promising method for differential diagnosis of HC and UHCE.
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