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Clinical observation of Myrtol Standardized Enteric Coated Soft Capsules combined with cefminox in treatment of acute suppurative sinusitis
Author(s): 
Pages: 1107-1110
Year: Issue:  9
Journal: World Phytomedicines

Keyword:  Myrtol Standardized Enteric Coated Soft CapsulesCefminox Sodium for injectionacute suppurative sinusitisnasal mucosa cilia transmission time;
Abstract: Objective To investigate the clinical efficacy of Myrtol Standardized Enteric Coated Soft Capsules combined with cefminox in treatment of acute suppurative sinusitis.Methods Patients (80 cases) with acute suppurative sinusitis in Department of Otolaryngology of the People’s Hospital of Bozhou from January 2012 to December 2014 were randomly divided into control and treatment groups, and each group had 40 cases. The patients in the control group were iv administered with Cefminox Sodium for injection, 1 g/time which added into physiological saline 20 mL, twice daily. The patients in the treatment group werepo administered with Myrtol Standardized Enteric Coated Soft Capsules on the basis of the control group, 1 grain/time, three times daily. The patients in two groups were treated for 6 weeks. After treatment, the efficacy was evaluated, the changes of nasal mucosa cilia transmission time before and after treatment in two groups were compared. Follow-up of 3 months, the recurrence rates in two groups were calculated.ResultsAfter the treatment, the efficacies in the control and treatment groups were 77.5% and 92.5%, respectively, and there was difference between two groups (P < 0.05). After treatment, nasal mucosa cilia transmission times in two groups were significantly reduced after 1 and 6 weeks, and the difference was statistically significant in the same group (P < 0.05). The reduced degree in the treatment group was better than that in the control group, with significant difference between two groups (P < 0.05). The recurrence rates in the control and treatment groups were 5% and 15%, respectively, and there was difference between two groups (P < 0.05).Conclusion Myrtol Standardized Enteric Coated Soft Capsules combined with cefminox has good clinical efficacy in treatment of acute suppurative sinusitis, and can significantly shorten the nasal mucosa cilia transmission time, which has high clinical application value.
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