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ji yu jiu bing ru luo li lun tan tao nan zhi xing shen bing zong he zheng zhong yi bing ji
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Pages: 1076-1079
Year: Issue:  7
Journal: Hebei Journal of Traditional Chinese Medicine

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Abstract: 难治性肾病综合征(refractory nephotic syndrome,RNS)是指经正规激素治疗,出现经常复发、肾上腺皮质激素依赖和肾上腺皮质激素抵抗之一的原发性肾病综合征(primary nephrotic syndrome,PNS)[1].RNS临床上极为常见,占PNS的30%~50%,是目前临床治疗比较棘手、预后较差的肾病[2-3].RNS经久不愈可诱发多种致命并发症,后期常进展慢性肾衰竭,最终发展为终末期肾病,其治疗缓解率与肾脏存活率呈正相关性,临床主张中西医并用[4].我们通过研究中医学经典文献并结合临床实践,发现根据RNS“难治性、缠绵性、反复性”的病证特点,运用中医“久病入络”理论阐释其发病病机,指导辨证论治,执简驭繁,验之于临床,可明显提高疗效,初步探讨如下.
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