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Effects of Huazhuo-tongluo formula on liver function, interleukin-6 and tumor necrosis-α in alcoholic hepatitis patients
Author(s): 
Pages: 980-982,1038
Year: Issue:  7
Journal: Hebei Journal of Traditional Chinese Medicine

Keyword:  Alcoholic hepatitisTraditional Chinese Medicine therapyInterleukin-6Tumor necrosis-α;
Abstract: 目的 观察化浊通络方对酒精性肝炎患者肝功能、白细胞介素6(IL-6)及肿瘤坏死因子α(TNF-α)的影响.方法 将70例酒精性肝炎患者随机分为2组,治疗组35例应用化浊通络方治疗,对照组35例应用水飞蓟宾葡甲胺片治疗.2组治疗3个月后比较疗效,观察2组治疗前后肝功能[丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)、γ-谷氨酰转移酶(γ-GT)及总胆红素(TBiL)]、IL-6及TNF-α变化,同时记录治疗前后患者主要症状改善情况.结果 2组显效率及总有效率比较差异均有统计学意义(P<0.05),治疗组疗效优于对照组;2组治疗后ALT、AST、γ-GT、TBiL、IL-6及TNF-α水平变化与本组治疗前比较均有明显阵低(P< 0.05),且治疗组降低更明显(P<0.05);2组主要症状改善率比较差异均有统计学意义(P<0.05),治疗组改善率优于对照组.结论 化浊通络方治疗酒精性肝炎疗效确切,可明显改善患者肝功能,降低血清IL-6、TNF-α水平,改善临床症状.
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