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Effects of Shuxuetong injection on liver function in patients with septic shock
Author(s): 
Pages: 987-989,1014
Year: Issue:  7
Journal: Hebei Journal of Traditional Chinese Medicine

Keyword:  LumbricusInfusionIntravenousLeechSepsisLiverInjection;
Abstract: 目的 观察疏血通注射液对脓毒症休克患者肝功能及预后的影响及临床疗效.方法 将80例脓毒症休克患者随机分为2组.对照组40例子积极的液体复苏、抗感染、保肝等常规治疗,治疗组40例在对照组治疗基础上加用疏血通注射液.2组均治疗7d.观察治疗前后肝功能指标[乳酸(LAC)、丙氨酸氨基转移酶(ALT)、天冬氨酸氨基转移酶(AST)]、急性生理功能和慢性健康状态评分系统Ⅱ(APACHEⅡ)评分、血管活性药物总用量(多巴胺、多巴酚丁胺及去甲肾上腺素)及28 d病死率.结果 2组治疗后LAC、AST、ALT与本组治疗前比较均降低(P<0.05),且治疗组降低优于对照组(P<0.05);治疗组多巴胺、多巴酚丁胺、去甲肾上腺素用量明显少于对照组(P<0.05);治疗组28 d病死率(40.0%)低于对照组(60.0%,P<0.05).结论 疏血通注射液可改善脓毒症休克患者肝功能,降低患者死亡率.
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