Author(s): Niu Lihui
Pages: 550-553
Year: 2015 Issue:  7
Journal: International Journal of Cerebrovascular Diseases
Keyword:  Brain Ischemia; Curcumin; Oxidative Stress; Antioxidants; Apoptosis; Brain Edema; Inflammation;
Abstract: Curcumin,a polyphenol compound,is a bioactive constituent extracted from the roots of the perennial herb Curcuma longa L.It has antioxidant,anti-inflammatory,anti-infective,heart protective and anti-tumor properties.Recent research has shown that curcumin can exert neuroprotective role in cerebral ischemia via the mechanisms of antioxidative stress,antiapoptosis,anti-cerebral edema,and anti-inflammation.This article reviews the neuroprotective mechanisms of curcumin in cerebral ischemia.