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Effect of Xuefuzhuyu capsules on the platelet aggregation in elder patients with chronic pulmonary heart disease complicated by type Ⅱ respiratory failure
Author(s): TAO Lihong, WANG Caiyun, Red Cross Hospital of Chongqing City, Department of Cardiology, the First Hospital Affiliated to University of South China
Pages: 924-
927
Year: 2015
Issue:
9
Journal: Jilin Journal of Traditional Chinese Medicine
Keyword: Xuefuzhuyu capsules; chronic pulmonary heart disease; type II respiratory failure; prognosis; platelet aggregation;
Abstract: Objective To investigate the effect of Xuefuzhuyu capsules in combined with bi-level positive airway pressure ventilation on the prognosis and platelet aggregation in elder patients with chronic pulmonary heart disease complicated by type II respiratory failure. Methods A total of 122 patients with chronic pulmonary heart disease complicated by type II respiratory failure who were admitted in our hospital from January,2013 to September,2014 were included in the study and randomized into the observation group( n = 61) and the control group( n = 61). The patients in the two groups were given the routine treatment in combined with bi-level positive airway pressure ventilation. On the above basis,the patients in the observation group were additionally administered with Xuefuzhuyu capsules. The therapeutic effect and the platelet aggregation before and after treatment in the two groups were compared. Results The total effective rate in the observation group( 96. 72%) was significantly higher than that in the control group( 85. 25%)( P < 0. 05). The average hospitalization time in the observation group( 10. 8 ± 5. 1) d was significantly shorter than that in the control group( 13. 2 ± 5. 9) d( P < 0. 05). The comparison of the mortality between the two groups was not statistically significant,but the mortality in the observation group was only 1. 64%,lower than that in the control group. The platelet aggregation rate after treatment in the two groups was significantly reduced when compared with that before treatment( P < 0. 05). The platelet aggregation rate after treatment in the observation group was significantly lower than that in the control group( P < 0. 05). Conclusions Xuefuzhuyu capsules in combined with bi-level positive airway pressure ventilation in the treatment of elder patients with chronic pulmonary heart disease complicated by type II respiratory failure can effectively improve the prognosis,and reduce the platelet aggregation with a favorable effect.
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