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Relationship between DBP Levels and Heart Rate Variability in Very Elderly Hypertensive Patients
Author(s): 
Pages: 1156-1158
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  very elderlydiastolic blood pressureheart rate variabilitylow-density lipoprotein-cholesterol;
Abstract: Objective To investigate the relationship between diastolic blood pressure and heart rate variability in very elderly hypertensive patients. Methods One hundred and sixty-nine very elderly hypertensive patients were divided into five groups according to 24 hours average diastolic blood pressure: Group 1( more than 80 mm Hg),group 2( 70 to 79 mm Hg),group 3( 60 to 69 mm Hg),group 4( 50 to 59 mm Hg),and group 5( < 50 mm Hg). The heart rate variability was determined by holter monitor and compared. Results The difference among low-density lipoprotein-cholesterol( LDL-C),SDNN,and RMSSD had statistically significant(P <0. 05 or P <0. 01). LDL-C: group 4 < group 5 < group 2 < group 3 < group 1. SDNN: group 1 < group 2 < group 3 < group4 < group 5. RMSSD: group 2 < group 1 < group 3 < group 4 < group 5. LDL-C were positively related to 24 h DBP(r = 0. 457,P =0. 000),SNDD and RMSSD was negative related to 24 h DBP(r =- 0. 304,P = 0. 000; r =- 0. 228,P = 0. 008). Multiple linear stepwise regression analysis showed that LDL-C and SDNN were the influencing factors of 24 h DBP. Conclusion The rise of diastolic blood pressure in very elderly hypertensive patients maybe result from both dysfunction of the autonomic nervous system and the rise in LDL-C.
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