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Effect of BNP on Cardiovascular Events and Prognosis in Patients with Chronic Heart Failure
Pages: 1159-1162
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  chronic heart failureB-type natriuretic peptidecardiovascular eventsprognosis;
Abstract: Objective To investigate the effect of B-type natriuretic peptide( BNP) on cardiovascular events and prognosis in patients with chronic heart failure( CHF). Methods One hundred and seventy-four patients with CHF from January 2009 to January 2013 with first onset were considered as study subjects. According to the levels of BNP,patients were divided into normal group and elevated BNP group. The cardiovascular events were compared between the two groups. According to the prognosis,patients were divided into death group and survival group. The general information were compared between the two groups,the influencing factors of prognosis single factor and multi factor. Results The mortality rate of hospitalization( 23. 19%),the rate of rehospitalization( 42. 75%) and hospitalization time in elevated BNP group were higher than those in the normal group(P < 0. 05). The death age of patients,duration of CHF,systolic blood pressure,left ventricular end diastolic diameter( LVEDd),BNP levels,and NYHA-Ⅴ grade in death group were higher than that in the survival group,left ventricular ejection fraction( LVEF),beta blocker use rate were lower than that in survival group(P < 0. 05). The levels of BNP,LVEF,beta blocker use,and classification of cardiac function had a significant impact on the prognosis of patients with CHF(P <0. 05). Conclusion The prognosis is closely related with the level of BNP in patients with CHF. BNP can serve as an important indicator to evaluate the prognosis in patients with CHF.
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