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bu tong yao wu zhi liao dui yu guan xin bing huan zhe xin shi zhong gou ji qt li san du de ying xiang
Author(s): 
Pages: 1190-1192
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  冠心病心室重构QT离散度螺内酯美托洛尔;
Abstract: 目的对比不同药物治疗对于冠心病患者心室重构及QT离散度的影响。方法冠心病患者80例根据随机抽签原则分为治疗组与对照组,每组40例,两组都给予介入治疗,介入前对照组给予美托洛尔治疗,治疗组给予螺内酯治疗,疗程为3个月。结果治疗组治疗后总有效率为97.5%,对照组为80.0%,治疗组明显高于对照组(P<0.05)。两组治疗后全血脑钠素含量、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD)、QT离散度较治疗前明显降低(P<0.05),治疗后治疗组全血脑钠素含量、LVESD、LVEDD、QT离散度明显低于对照组(P<0.05)。结论相对于美托洛尔,螺内酯在冠心病患者中的应用能有效逆转心室重构状况,降低全血脑钠素含量,缩短QT离散度,从而提高总体治疗疗效。
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