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shu xue tong zhu she ye dui ami ji zhen xing jing pi guan zhuang dong mai jie ru shu hou wu fu liu bing ren xin gong neng de ying xiang
Author(s): 
Pages: 1193-1195
Year: Issue:  10
Journal: Research of Traditional Chinese Medicine

Keyword:  急性心肌梗死疏血通注射液术后无复流心功能;
Abstract: 目的观察疏血通注射液对急性心肌梗死病人急诊行经皮冠状动脉介入治疗(PCI)术后无复流,经治疗血流再通后的心功能的影响。方法选取我院急性心肌梗死早期急诊PCI的430例病人,其中43例病人置入支架后出现血流无复流现象,无复流病人中40例给予相应治疗血流再灌注达心肌梗死后溶栓治疗试验(TIMI)血流分级3级,随机分为疏血通注射液治疗组和传统治疗的对照组,每组20例。观察治疗前后超声心动图指标和血浆N端脑钠肽前体(NT-proBNP)浓度变化及不良事件。结果治疗组治疗后血浆NT-proBNP浓度、左室射血分数(LVEF)及重症监护病房(CCU)住院时间均显著好于对照组(P<0.05),用药前后两组肝肾功能、凝血指标未发现有临床意义的变化。结论疏血通注射液可改善急性心肌梗死急诊PCI术无复流后血流再通病人的心功能。
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