Advances in the treatment of JAK2 V617F gene mutation positive myeloproliferative neoplasms
Author(s): Lin Fengru, Wang Yan, Zhang Jingyu
Pages: 392-393
Year: 2015 Issue: 7
Journal: Journal of Leukemia & Lymphoma
Keyword: Myeloproliferative neoplasms; JAK2 V617F gene mutation; Therapy;
Abstract: JAK2 V617F gene mutation positive myeloproliferative neoplasms (MPN) consists of polycythemia vera (PV),essential thrombocythemia (ET) and primary myelofibrosis (PMF).This article focuses on their risk scoring systems and treatment including first-and second-line therapies,JAK2 inhibitors,cytoreduction,antifibrosis and other single-agent or combination therapy.
Pages: 392-393
Year: 2015 Issue: 7
Journal: Journal of Leukemia & Lymphoma
Keyword: Myeloproliferative neoplasms; JAK2 V617F gene mutation; Therapy;
Abstract: JAK2 V617F gene mutation positive myeloproliferative neoplasms (MPN) consists of polycythemia vera (PV),essential thrombocythemia (ET) and primary myelofibrosis (PMF).This article focuses on their risk scoring systems and treatment including first-and second-line therapies,JAK2 inhibitors,cytoreduction,antifibrosis and other single-agent or combination therapy.
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