Author(s): GU Muqing, XIAO Fengjuan, LIANG Ye, YUE Lin, LI SONG LI Lanlan, FENG Feifei, School of Material Science and Engineering, Shijiazhuang Tiedao University
Pages: 826-831
Year: 2015 Issue:  4
Journal: Journal of Biomedical Engineering
Keyword:  hydroxyapatite; polyurethane; micro morphology; thermal stability; mechanical properties; biocompatibility;
Abstract: In order to improve the interfacial bonding strength of hydroxyapatite/polyurethane implanted material and dispersion of hydroxyapatite in the polyurethane matrix,we in the present study synthesized nano-hydroxyapatite/polyurethane composites by in situ polymerization.We then characterized and analyzed the fracture morphology,thermal stability,glass transition temperature and mechanical properties.We seeded MG63 cells on composites to evaluate the cytocompatibility of the composites.In situ polymerization could improve the interfacial bonding strength,ameliorate dispersion of hydroxyapatite in the properties of the composites.After adding 20 wt%hydroxyapatite into the polyurethane,the thermal stability was improved and the glass transition temperatures were increased.The tensile strength and maximum elongation were 6.83 MPa and 861.17%,respectively.Compared with those of pure polyurethane the tensile strength and maximum elongation increased by 236.45% and 143.30%,respectively.The composites were helpful for cell adhesion and proliferation in cultivation.