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Clinical Research of Pingtang Gushen Fang in Treating Early Diabetic Nephropathy
Pages: 1261-1263
Year: Issue:  9
Journal: China Journal of Chinese Medicine

Keyword:  diabetic nephropathypingtang gushen fangblood-fasting sugararterial blood pressureglycosylated hemoglobinrenal;
Abstract: Objective:To investigate the clinical curative effect of Pingtang Gushen Fang in treating early diabetic nephropathy(DN). Methods:50 cases of early DN were randomly divided into control group(25 cases)and treatment group(25 cases). The control group was administrated conventional hypoglycemic agent and treatment group was treated with Pingtang Gushen Fang. Compared the level of fasting blood glucose(FBG),blood pressure,blood urea nitrogen,selxlm creatinine(Cr),urine albumin,urine total protein(UTP),to-tal cholesterol(TC),triglyefide(TG),high density lipoprotein(HDL-C),low density lipoprotein(LDL-C)of two groups before and after therapy. Results:Compared FBG,glycosylated hemoglobin and arterial blood pressure of two groups,there was no significant differ-ence. The urine small protein,total protein,creatinine and urea nitrogen level of two groups were significantly decreased compared with before,especially treatment group. The level of TC,TG,and LDL-C significantly decreased and HDL-C significantly increased. All index in treatment group were significantly improved well(P ﹤ 0. 05). Conclusion:Pingtang Gushen Fang combined with routine hypoglycemic agents could significantly improve blood lipid,decrease urine protein,improve rental function and has good curative effect on DN.
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