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Influence of Luffa Decoction on the Immune Function of Mice
Pages: 1319-1321
Year: Issue:  9
Journal: China Journal of Chinese Medicine

Keyword:  luffa water decoctionimmune functionmice;
Abstract: Objective:To explore the influence of Luffa decoction on the immune function of mice. Methods:375 mice were randomly di-vided into blank control group,luffa decoction of low concentration group(2. 5 g·kg - 1 ),middle concentration group(5. 0 g·kg - 1 ), high concentration and high concentration group(10 g·kg - 1 ),prednisone group(0. 025 g·kg - 1 ). Used ear swelling test,Tanguo-qing test,splenic lymphocyte transformation test,lymphocyte a-naphthalene acetic acid esterase staining method and the content test of serum IgG and IgM to explore the influence of the Luffa decoction on the immune function of mice. Results:The Luffa decoction (10 g·kg - 1 )can significantly reduce delayed-type hypersensitivity of mice(P ﹤ 0. 01),inhibit the activity of mononuclear macro-phage of mice(P ﹤ 0. 01),reduce the lymphocyte conversion rate(P ﹤ 0. 01),reduce blood T lymphocytes in mice(P ﹤ 0. 01)and significantly reduce the serum IgG and IgM in mice(P ﹤ 0. 01). Conclusion:The high concentration of luffa decoction(10 g·kg - 1 ) has significant inhibition of the immune function of mice.
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