Expression and significance of NT-proBNP and troponin I in patients of chronic pulmonary heart disease decompensated stage
Author(s): LUO Jian-li
Pages: 3-4,5
Year: 2015 Issue: 23
Journal: China Practical Medical
Keyword: Chronic pulmonary heart disease; Compensated stage; N-terminal pro brain natriuretic peptide; Troponin I;
Abstract: Objective To analyze expression and clinical significance of N-terminal pro brain natriuretic peptide (NT-proBNP) and troponin I in patients of chronic pulmonary heart disease decompensated stage. Methods A total of 97 patients with chronic pulmonary heart disease were divided by disease condition into compensated stage group with 61 cases and decompensated stage group with 36 cases. Another 28 healthy people were chosen as control group. Pulmonary function indexes of these groups were evaluated, and expression levels of NT-proBNP and troponin I were detected. Results The decompensated stage group had statistically significant differences with the compensated stage group and the control group in forced expiratory volume in 1 second (FEV1), proportion of forced expiratory volume in 1 second in forced vital capacity (FEV1/FVC), peak expiratory flow (PEF), and forced vital capacity (FVC) (P<0.05). The decompensated stage group also had obviously higher NT-proBNP and troponin I than the compensated stage group and the control group, and their difference had statistical significance (F=326.2, 299.6, P<0.05). Conclusion NT-proBNP and troponin I may be involved in occurrence and progression of chronic pulmonary heart disease, and they provides certain experimental evidence for early diagnosis of chronic pulmonary heart disease.
Pages: 3-4,5
Year: 2015 Issue: 23
Journal: China Practical Medical
Keyword: Chronic pulmonary heart disease; Compensated stage; N-terminal pro brain natriuretic peptide; Troponin I;
Abstract: Objective To analyze expression and clinical significance of N-terminal pro brain natriuretic peptide (NT-proBNP) and troponin I in patients of chronic pulmonary heart disease decompensated stage. Methods A total of 97 patients with chronic pulmonary heart disease were divided by disease condition into compensated stage group with 61 cases and decompensated stage group with 36 cases. Another 28 healthy people were chosen as control group. Pulmonary function indexes of these groups were evaluated, and expression levels of NT-proBNP and troponin I were detected. Results The decompensated stage group had statistically significant differences with the compensated stage group and the control group in forced expiratory volume in 1 second (FEV1), proportion of forced expiratory volume in 1 second in forced vital capacity (FEV1/FVC), peak expiratory flow (PEF), and forced vital capacity (FVC) (P<0.05). The decompensated stage group also had obviously higher NT-proBNP and troponin I than the compensated stage group and the control group, and their difference had statistical significance (F=326.2, 299.6, P<0.05). Conclusion NT-proBNP and troponin I may be involved in occurrence and progression of chronic pulmonary heart disease, and they provides certain experimental evidence for early diagnosis of chronic pulmonary heart disease.
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