Author(s): WANG Jian, SONG Xiuyu, XU Wengui, ZHOU Wen
Pages: 361-365
Year: 2015 Issue:  4
Journal: International Journal of Medical Radiology
Keyword:  Breast cancer; Positron emission mammography; Radionuclide; Tracer imaging;
Abstract: With the developments of new type specific imaging agent and imaging device, the molecular imaging technology of breast cancer is being developed rapidly. Radionuclide molecular imaging techniques for breast cancer include single photon emission tomography (SPECT) and positron emission body tomography (PET), PET/CT and positron emission (PEM) imaging. In addition to the most widely used radiotracer 18F -FDG, for study of tumor cell proliferation imaging 5-18F-FU and FLT can be used. For imaging tumor amino acid metabolism, RGD-based tracers are available. The receptor-targeted agents include estrogen receptor related FES, radiolabeled human epidermal growth factor receptor 2 (HER2) and epidermal growth factor receptor (EGFR). At present, the PEM technique had an important clinical value in the early diagnosis and prognosis prediction of breast cancer. We reviewed the research progress of the radionuclide molecular imaging for breast cancer.