ANTIBIOTICS PRODUCED BY SOIL FUNGUS STRAIN C3368 FROM ANTARCTICA I. TAXONOMY OF STRAIN C3368,FERMENTATION AND BIOLOGICAL ACTIVITY OF ANTIBIOTICS
Author(s): Cheng Yong-qing, Hu Ji-lan and Qi Chang-qing
Pages: 401-403
Year: 1992 Issue: 6
Journal: Chinese Journal of Antibiotics
Keyword: Antarctica; Chrysosporium verrucosum Tubaki C3368; Nucleoside transport inhibitory effect; Nucleoside absorption inhibitory effect;
Abstract: Strain C3368,a fungus isolated from a soil sample collectedin King George Island of Antarctica was found to produce the antibiotics. R-( - )-Bisdechlorogeodin(C3368-A) and Questin (C3368-B) .From taxono-mic studies on its morphological, cultural characteristics, this antibiotic-producing strain was identified as Chrysosporium verrucosum Tubaki C3368. Antibiotic C3368-A and B showed very strong inhibitory effect onnucleoside transport of tumor cell and nucleoside absorption of mouse spleen lymphocyte.It is a first example that from metabolite products of Antarctic soil fungi to find antibiotic having activity described above.
Pages: 401-403
Year: 1992 Issue: 6
Journal: Chinese Journal of Antibiotics
Keyword: Antarctica; Chrysosporium verrucosum Tubaki C3368; Nucleoside transport inhibitory effect; Nucleoside absorption inhibitory effect;
Abstract: Strain C3368,a fungus isolated from a soil sample collectedin King George Island of Antarctica was found to produce the antibiotics. R-( - )-Bisdechlorogeodin(C3368-A) and Questin (C3368-B) .From taxono-mic studies on its morphological, cultural characteristics, this antibiotic-producing strain was identified as Chrysosporium verrucosum Tubaki C3368. Antibiotic C3368-A and B showed very strong inhibitory effect onnucleoside transport of tumor cell and nucleoside absorption of mouse spleen lymphocyte.It is a first example that from metabolite products of Antarctic soil fungi to find antibiotic having activity described above.
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