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jian xun
Author(s): 
Pages: 63
Year: Issue:  4
Journal: Chinese Journal of Antibiotics

Keyword:  己内酰胺丁二醇仲丁醇英国专利头抱菌素林肯霉素丁酮可由利福霉素肝脏损害;
Abstract: <正> 头孢菌素C的发酵培养基 以头孢霉菌(Cephalosporium sp.)发酵生产头孢菌素C,当培养基中加入ε-己内酰胺、2-丁酮、仲丁醇或1.3-丁二醇等类化合物中的一种或多种时,可增加头孢菌素C的产量。如头孢霉菌I.B.I.1131在每升含有2.5克的ε-己内酰胺的培养基中培养,头孢菌素 C的产量可由 1950微克/毫升增加到3015微克/毫升,最合适的加入物及加入量是0.5-5克ε-己内酰胺、1-20毫升2一丁酮或仲丁醇及1-15毫升1.3-丁二醇。
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