Clinical observation of Xiaoer Zhili Syrup combined with Methylphenidate Hydrochloride Tablets in treatment of attention deficit hyperactivity disorder
Author(s): ZHU Xiao-bing, Derpartment of Paediatrics, The People’s Hospital of Kaixian County in Chongqing
Pages: 829-832
Year: 2015 Issue: 7
Journal: World Phytomedicines
Keyword: Xiaoer Zhili Syrup; Methylphenidate Hydrochloride Tablets; attention deficit hyperactivity disorder; Conner behavior rating scale;
Abstract: Objective To investigate the clinical effect of Xiaoer Zhili Syrup combined with Methylphenidate Hydrochloride Tablets in treatment of attention deficit hyperactivity disorder. Methods Patients(90 cases) with attention deficit hyperactivity disorder in the derpartment of paediatrics of People’s Hospital of Kaixian County in Chongqing from January 2012 to December 2014 were randomly divided into control and treatment groups. Each group had 45 cases. Patients in control group were po administered with Methylphenidate Hydrochloride Tablets, 2 tablets/time, once daily. Patients in treatment group were po administered with Xiaoer Zhili Syrup on the basis of the control group, 10 m L/time, twice daily. A course of treatment included 3 weeks, and the patients in two groups maintained the treatment for three coures. After treatment, the efficacy was evaluated, and the changes of each factor score in Conner behavior rating scale and adverse reactions in two groups before and after treatment were compared. Results The efficacies in the control and treatment groups were 77.78% and 88.89%, respectively, and there were differences between two groups(P < 0.05). After treatment, scores of impulse hyperactivity, index of hyperactivity, learning problems, character, anxiety, physical and mental problems in two groups were significantly reduced, and the difference was statistically significant in the same group(P < 0.05). And these indicators in the treatment group improved better than those in the control group, with significant difference between two groups(P < 0.05). Conclusion Xiaoer Zhili Syrup combined with Methylphenidate Hydrochloride Tablets can significantly improve the clinical curative effect in treatment of attention deficit hyperactivity disorder with no serious adverse reaction, which has a certain clinical value.
Pages: 829-832
Year: 2015 Issue: 7
Journal: World Phytomedicines
Keyword: Xiaoer Zhili Syrup; Methylphenidate Hydrochloride Tablets; attention deficit hyperactivity disorder; Conner behavior rating scale;
Abstract: Objective To investigate the clinical effect of Xiaoer Zhili Syrup combined with Methylphenidate Hydrochloride Tablets in treatment of attention deficit hyperactivity disorder. Methods Patients(90 cases) with attention deficit hyperactivity disorder in the derpartment of paediatrics of People’s Hospital of Kaixian County in Chongqing from January 2012 to December 2014 were randomly divided into control and treatment groups. Each group had 45 cases. Patients in control group were po administered with Methylphenidate Hydrochloride Tablets, 2 tablets/time, once daily. Patients in treatment group were po administered with Xiaoer Zhili Syrup on the basis of the control group, 10 m L/time, twice daily. A course of treatment included 3 weeks, and the patients in two groups maintained the treatment for three coures. After treatment, the efficacy was evaluated, and the changes of each factor score in Conner behavior rating scale and adverse reactions in two groups before and after treatment were compared. Results The efficacies in the control and treatment groups were 77.78% and 88.89%, respectively, and there were differences between two groups(P < 0.05). After treatment, scores of impulse hyperactivity, index of hyperactivity, learning problems, character, anxiety, physical and mental problems in two groups were significantly reduced, and the difference was statistically significant in the same group(P < 0.05). And these indicators in the treatment group improved better than those in the control group, with significant difference between two groups(P < 0.05). Conclusion Xiaoer Zhili Syrup combined with Methylphenidate Hydrochloride Tablets can significantly improve the clinical curative effect in treatment of attention deficit hyperactivity disorder with no serious adverse reaction, which has a certain clinical value.
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