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Relationship between Telomere,Telomerase and Vascular Aging
Author(s): 
Pages: 893-896
Year: Issue:  7
Journal: Research of Traditional Chinese Medicine

Keyword:  telomeretelomerasevascular agingaging;
Abstract: The research of vascular aging problem with age has become a new target for the prevention and treatment of cardiovascular disease.Vascular aging,which pathological changes mainly involved in endothelial cells and smooth muscle cells senescence,is a degenerative disease.The telomere hypothesis is one of the widely discussed hypothesis of senescence,the shortening of telomere length is considered to be the start of cellular senescence;telomerase is a ribonucleoprotein complex special,which can effectively maintain telomere length in order to delay aging.And then we speculated that telomere and telomerase may be contact closely with vascular ageing through the form of cell senescence.
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