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A Randomized Controlled Trial of Lizhuchangle and Cisapride In Treatment of Habitual Constipation
Author(s): 
Pages: 123-124
Year: Issue:  3
Journal: CHINESE JOURNAL OF PHARMACOEPIDEMIOLOGY

Keyword:  丽珠肠乐西沙比利便秘随机对照试验;
Abstract: 目的: 探讨丽珠肠乐、西沙比利联用治疗习惯性便秘的疗效和安全性. 方法: 将128例习惯性便秘患者随机分为: A组48例,为丽珠肠乐、西沙比利联用治疗组; B组42例, 为丽珠肠乐组; C组38例, 为大黄苏打片组. 观察近期疗效、远期复发率和副作用. 结果:近期疗效: A组治愈率87.5%; B组治愈率80.95%; C组治愈率76.32%. 三组互相比较P>0.05. 6个月后远期总复率:A组9.52%, B组29.42%, C组89.56%, A组与B组比P<0.05, B组与C组比P<0.01, A组与C组比P<0.01. 结论:近期疗效, 丽珠肠乐、西沙比利无论合用、单用, 都与服用大黄苏打片差异显著. 远期复发率三组之间差异显著, 丽珠肠乐与西沙比利联用组复发率最低.
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