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Relationship between the levels of EGF,IL-6,TNF-α and the survival of lung cancer
Author(s): 
Pages: 237-238,268
Year: Issue:  3
Journal: CHINA ONCOLOGY

Keyword:  EGFIL-6TNF -α肺癌;
Abstract: 目的:探讨表皮生长因子(EGF)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)等3种细胞因子的含量与肺癌及其预后的关系.方法:取明确诊断为肺癌的患者术前和术后血清以及手术中肺癌及肺周围组织标本进行细胞因子的检测,同时进行该组患者肺癌复发和转移的观察.结果:TNF-α在肺癌组织与肺周边组织中含量无明显变化,EGF在癌组织中存活组与死亡组比较其含量差异有显著性(P<0.05),IL-6在肺组织中存活组与死亡组比较其含量差异有显著性(P<0.05).结论:EGF、IL-6的变化与肺癌患者的生存期有一定关系,而TNF-α与本组患者的生存期似无明显关系.
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